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Kenneth R Chien Selected Research

cysteine and glycine-rich protein 3

3/2010A common MLP (muscle LIM protein) variant is associated with cardiomyopathy.
12/2007Angiotensin II type 1a receptor signals are involved in the progression of heart failure in MLP-deficient mice.
8/2005Young MLP deficient mice show diastolic dysfunction before the onset of dilated cardiomyopathy.
1/2002Muscle LIM protein in heart failure.

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Kenneth R Chien Research Topics

Disease

20Heart Failure
01/2022 - 01/2002
8Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2021 - 08/2002
6Cardiomyopathies (Cardiomyopathy)
01/2021 - 06/2002
4Heart Diseases (Heart Disease)
01/2022 - 01/2008
4Myocardial Infarction
06/2018 - 07/2006
3Congenital Heart Defects (Congenital Heart Defect)
01/2019 - 09/2009
3Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
03/2010 - 01/2004
3Cardiomegaly (Heart Hypertrophy)
09/2009 - 10/2004
3Ischemia
01/2006 - 09/2004
3Hypertrophy
08/2004 - 03/2003
2Cardiovascular Diseases (Cardiovascular Disease)
01/2019 - 09/2007
2Wounds and Injuries (Trauma)
01/2019 - 11/2018
2Neoplasms (Cancer)
09/2011 - 06/2002
2Disease Progression
09/2009 - 12/2007
2Infections
11/2006 - 02/2003
2Infarction (Infarctions)
07/2006 - 03/2004
2Fibrosis (Cirrhosis)
01/2006 - 08/2004
1Cicatrix (Scar)
01/2022
1Chronic Limb-Threatening Ischemia
01/2019
1Type 2 Diabetes Mellitus (MODY)
01/2019
1Necrosis
01/2019
1Diabetic Cardiomyopathies
11/2014
1Ventricular Heart Septal Defects (Ventricular Septal Defect)
07/2011
1Atrial Heart Septal Defects (Atrial Septal Defect)
07/2011
1Left Ventricular Dysfunction
09/2009
1Atrioventricular Block
09/2009
1Virus Diseases (Viral Diseases)
11/2006
1Acute Promyelocytic Leukemia
10/2006
1Vascular Remodeling
09/2006
1Hypoxia (Hypoxemia)
01/2006
1Myotonic Dystrophy (Dystrophia Myotonica)
03/2005
1Familial Hypertrophic Cardiomyopathy (Cardiomyopathy, Familial Hypertrophic)
08/2004
1Obesity
07/2004
1Insulin Resistance
07/2004
1Body Weight (Weight, Body)
07/2004
1Neutropenia
02/2004
1Absence Epilepsy (Childhood Absence Epilepsy)
01/2003
1Cardiac Sudden Death (Sudden Cardiac Arrest)
01/2003
1Cutis Laxa
10/2002
1Emphysema
10/2002

Drug/Important Bio-Agent (IBA)

7Messenger RNA (mRNA)IBA
01/2022 - 09/2011
7CalciumIBA
01/2022 - 05/2003
6Proteins (Proteins, Gene)FDA Link
01/2022 - 03/2004
5phospholambanIBA
01/2022 - 08/2002
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2019 - 01/2006
4cysteine and glycine-rich protein 3IBA
03/2010 - 01/2002
3Peptides (Polypeptides)IBA
09/2007 - 03/2004
3CytokinesIBA
11/2006 - 11/2004
2Pharmaceutical PreparationsIBA
11/2014 - 02/2008
2Transcription Factors (Transcription Factor)IBA
07/2011 - 01/2003
2TamoxifenFDA LinkGeneric
07/2011 - 09/2009
2Laminin (Merosin)IBA
07/2007 - 01/2006
2IntegrinsIBA
07/2007 - 01/2006
2Antiviral Agents (Antivirals)IBA
11/2006 - 02/2003
2Trastuzumab (Herceptin)FDA Link
02/2006 - 06/2002
1Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA
01/2022
1Antisense OligonucleotidesIBA
01/2021
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2019
1BoronIBA
11/2018
1Oxygen (Dioxygen)IBA
11/2018
1RNA (Ribonucleic Acid)IBA
10/2013
1CatecholaminesIBA
03/2010
1Homeodomain Proteins (Proteins, Homeobox)IBA
09/2009
1Type 1 Angiotensin ReceptorIBA
12/2007
1Angiotensin IIIBA
12/2007
1integrin-linked kinaseIBA
07/2007
1InterferonsIBA
11/2006
1DystrophinIBA
11/2006
1Retinoic Acid Receptor alphaIBA
10/2006
1Therapeutic UsesIBA
07/2006
1Protein Kinases (Protein Kinase)IBA
03/2005
1Caveolin 3IBA
12/2004
1junctophilinIBA
12/2004
12,2,2',4'-tetrachloroacetophenoneIBA
12/2004
1Interleukin-6 (Interleukin 6)IBA
11/2004
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2004
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
10/2004
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2004
1Diazoxide (Hyperstat)FDA Link
09/2004
1Adenosine (Adenocard)FDA LinkGeneric
09/2004
1Carrier Proteins (Binding Protein)IBA
08/2004
1Cardiac MyosinsIBA
08/2004
1Dihydrotachysterol (AT 10)IBA
08/2004
1LeptinIBA
07/2004
1Pro-Opiomelanocortin (Proopiomelanocortin)IBA
07/2004
1Tyrosine (L-Tyrosine)FDA Link
07/2004
1Hormones (Hormone)IBA
07/2004
1UrocortinsIBA
03/2004
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/2004
1Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
01/2004
1Monomeric GTP-Binding ProteinsIBA
01/2004
1Elastomers (Elastomer)IBA
03/2003
1Hyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsIBA
01/2003
1fibulinIBA
10/2002

Therapy/Procedure

11Therapeutics
01/2019 - 06/2002
3Drug Therapy (Chemotherapy)
01/2013 - 06/2002
2Transplantation
01/2022 - 01/2018
2Cell- and Tissue-Based Therapy (Cell Therapy)
02/2008 - 07/2007
1Intradermal Injections
01/2019
1Injections
09/2009